It is located in the north of the Great Mosque and right next to the mosque. It is understood from the inscription on the construction of Artuqid Emir Ebu Muzaffer Sökmen in 1198. The stone pillars placed on both sides of the niche in the courtyard of the madrasa, which is a valuable work of art with its embellishments and inscriptions, were placed in the building to determine the collapse. The building is made of two floors of cut stone. Mesudiye Madrasah is the first university in Anatolia to study in.